HCID 58413265、化合物 → HCID 58413388、化合物
反応式
[N+:1]([C:4]1[C:5]([O:10][CH2:11][C:12]2([CH2:15][C:16]#[N:17])[CH2:14][CH2:13]2)=[N:6][CH:7]=[CH:8][CH:9]=1)([O-])=O>C(O)(=O)C.C(O)C>[NH2:1][C:4]1[C:5]([O:10][CH2:11][C:12]2([CH2:15][C:16]#[N:17])[CH2:14][CH2:13]2)=[N:6][CH:7]=[CH:8][CH:9]=1参加物
4
反応条件
- 温度
- 100 °C
実験手順
2-(1-((3-Nitropyridin-2-yloxy)methyl)cyclopropyl)acetonitrile (466 mg) was dissolved in a mixture of glacial acetic acid (4 ml) and ethanol (8 ml). Ferrum (1.1 g) was added and the reaction mixture was heated to 100° C. for 2 h. The mixture was concentrated in vacuo and the residue was dissolved in dichloromethane, extracted with an aqueous solution of K2CO3 (2M) and concentrated in vacuo
後処理
- additionFerrum (1.1 g) was added
- concentrationThe mixture was concentrated in vacuo
- dissolutionthe residue was dissolved in dichloromethane
- extractionextracted with an aqueous solution of K2CO3 (2M)
- concentrationconcentrated in vacuo
出典と根拠
- ORDレコード
- ord-fbc49b9bc15f46289377696a5fa1cada
- 出典データセット
- uspto-grants-2014_10
- 特許番号
- US08853193B2
反応ノート
読み込み中…