Sulfamide → HCID 11379214、化合物
反応式
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[O:3][CH:2]1[CH2:10][NH2:11].[S:12](N)([NH2:15])(=[O:14])=[O:13]>O1CCOCC1>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[O:3][CH:2]1[CH2:10][NH:11][S:12]([NH2:15])(=[O:14])=[O:13]参加物
4
実験手順
C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.
後処理
- temperaturethe solution was heated
- temperatureto reflux overnight
- concentrationThe reaction was concentrated
- customthe residue was chromatographed (2% to 10% acetone in dichloromethane)
出典と根拠
- ORDレコード
- ord-11eb86101c0f45bf96c6e3f8a3d40045
- 出典データセット
- uspto-grants-2014_10
- 特許番号
- US08853263B2
反応ノート
読み込み中…