Glyceryl Allyl Ether → 4-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine

HRID 534662

反応式

HRID 534662 の反応式
[CH3:1][N:2]([As:4](N(C)C)N(C)C)[CH3:3].[CH2:11]([O:14][CH2:15][CH:16]([OH:19])[CH2:17][OH:18])[CH:12]=[CH2:13]>CCCCCC>[CH2:11]([O:14][CH2:15][CH:16]1[CH2:17][O:18][As:4]([N:2]([CH3:3])[CH3:1])[O:19]1)[CH:12]=[CH2:13]

参加物

4

反応物 2

HCID 78950Glyceryl Allyl EtherHCID 165514N-[bis(dimethylamino)arsanyl]-N-methylmethanamine

生成物 1

HCID 867176874-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

実験手順

is formed when at room temperature, about 0.5 g (0.445 mL, 2.414 mmol, 1.1 equivalents) of tris(dimethylamino)arsine (TDMA), is added to about 10 mL dry hexane in a 25 mL round-bottom flask, and then about 0.29 g (0.27 mL, 2.19 mmol, 1.0 equivalents) of 3-(allyloxy)propane-1,2-diol is added dropwise into the system. The mixture is heated to reflux under nitrogen for about one hour, and then cooled to room temperature. Removal of the solvent in vacuum gives crude 4-((allyloxy)methyl)-N,N-dimethyl-1,3,2-dioxarsolan-2-amine as an oil.

後処理

  1. customis formed when at room temperature
  2. temperatureThe mixture is heated
  3. temperatureto reflux under nitrogen for about one hour
  4. customRemoval of the solvent in vacuum

出典と根拠

ORDレコード
ord-d965bae987d640fdb842bd4418f8dac3
出典データセット
uspto-grants-2014_10
特許番号
US08853438B2

関連ノート

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