(3-Chloro-5-(trifluoromethyl)phenyl)methanol → [3-Bromo-5-(trifluoromethyl)phenyl]methanol
反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:11]=1)[C:5](OC)=[O:6].ClC1C=C(CO)C=C(C(F)(F)F)C=1>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:5][OH:6])[CH:9]=[C:10]([C:12]([F:14])([F:15])[F:13])[CH:11]=1参加物
3
実験手順
The title compound was prepared from methyl 3-bromo-5-(trifluoromethyl)benzoate (Reference Example 37) by a procedure similar to the one described for (3-chloro-5-(trifluoromethyl)phenyl)methanol (Reference Example 30) to provide (3-bromo-5-(trifluoromethyl)phenyl)methanol (7.42 g, 35% (2 steps)) as a yellow oil.
出典と根拠
- ORDレコード
- ord-e6c46743bfe84d0ca0ba5b422a1fe056
- 出典データセット
- uspto-grants-2014_10
- 特許番号
- US08853215B2
反応ノート
読み込み中…