1-Bromo-2,5-dimethyl-4-nitrobenzene → tert-Butyl 3-(2,5-dimethyl-4-nitrophenyl)azetidine-1-carboxylate

HRID 536346ノート

反応式

HRID 536346 の反応式
I[CH:2]1[CH2:5][N:4]([C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])[CH2:3]1.Br[C:14]1[CH:19]=[C:18]([CH3:20])[C:17]([N+:21]([O-:23])=[O:22])=[CH:16][C:15]=1[CH3:24]>>[CH3:24][C:15]1[CH:16]=[C:17]([N+:21]([O-:23])=[O:22])[C:18]([CH3:20])=[CH:19][C:14]=1[CH:2]1[CH2:5][N:4]([C:6]([O:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])[CH2:3]1

参加物

3

反応物 2

HCID 8258081-Bromo-2,5-dimethyl-4-nitrobenzeneHCID 11000522Tert-butyl 3-iodoazetidine-1-carboxylate

生成物 1

HCID 86653270tert-Butyl 3-(2,5-dimethyl-4-nitrophenyl)azetidine-1-carboxylate

実験手順

Prepared from tert-butyl 3-iodoazetidine-1-carboxylate and 1-bromo-2,5-dimethyl-4-nitrobenzene by following the general protocol as described in Billotte, S. Synlett 1998, 379.

出典と根拠

ORDレコード
ord-2b43e6fab4dd49cd8491a7f0fed4c7ef
出典データセット
uspto-grants-2014_10
特許番号
US08859574B2

反応ノート

読み込み中…