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2-Chlorocinnamaldehyde → HCID 131731951、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chlorocinnamaldehyde | HCID 3014042 | — |
| 反応物 | 2-(Pyridin-4-yl)propanal | HCID 11480472 | — |
| 反応物 | Tert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate | HCID 131731949 | — |
| 生成物 | HCID 131731951 | HCID 131731951 | — |
反応手順
tert-Butyl{1-[(4-methylpiperidin-1-yl)carbonyl]-3-pyridin-4-ylpropyl}carbamate is prepared from pyridin-4-yl propionaldehyde (Kitbunnadaj, R. et al. J. Med. Chem, 2004, 47, 2414-2417) in the same manner that tert-butyl{3-(2-chlorophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate is prepared from 3-(2-chlorophenyl)propenal in Example 5.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08859814B2 |
| 出典データセット | uspto-grants-2014_10 |
| ORD ID | ord-61a3f82598af46388a71da91639c2d65 |
| 出典メモ | uspto-grants-2014_10 |