化工社化工社 化学情報印刷レポート · 研究参考用
Hexane → 2,6-Di-tert-butyl-4-(2-nitrostyryl)phenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hexane | HCID 8058 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 3,5-Di-tert-butyl-4-hydroxybenzaldehyde | HCID 73219 | — |
| 反応物 | (2-Nitrophenyl)acetic acid | HCID 77337 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 2,6-Di-tert-butyl-4-(2-nitrostyryl)phenol | HCID 54141749 | 62.9% |
反応手順
To a solution of 3,5-di-tert-butyl-4-hydroxybenzaldehyde (8.09 g, 34.5 mmol) and 2-nitrophenylacetic acid (9.40 g, 51.9 mmol) in xylene (60 ml) was added piperidine (0.3 ml) and the mixture was heated under reflux for 26 hrs while removing water producing with the progress of reaction. After allowing to stand overnight, hexane was added to afford as crystals 2,6-di-tert-butyl-4-(2-nitrostyryl)phenol (7.67 g, 62.9%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05621010 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-3925ace3a9be4734b0ae067507043c4f |
| 出典メモ | uspto-grants-1997_04 |