Acetic Acid → N-Benzylacetamide

HRID 538954

反応式

HRID 538954 の反応式
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:9](O)(=[O:11])[CH3:10]>>[C:9]([NH:8][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:11])[CH3:10]

参加物

3

反応物 2

HCID 176Acetic AcidHCID 7504Benzylamine

生成物 1

HCID 11500N-Benzylacetamide

反応条件

温度
115 °C

実験手順

Benzylamine (1 mL) and acetic acid (20 mL) may be mixed together. The mixture may be heated at 115° C. for 17 hours. The excess acetic acid may be distilled from the reaction mixture using a rotary evaporator. The product may be crystallized from toluene. The mixture may be cooled to 0° C. and then filtered.

後処理

  1. distillationThe excess acetic acid may be distilled from the reaction mixture
  2. customa rotary evaporator
  3. customThe product may be crystallized from toluene
  4. temperatureThe mixture may be cooled to 0° C.
  5. filtrationfiltered

出典と根拠

ORDレコード
ord-27a2c44870504edb8d0db479262b468b
出典データセット
uspto-grants-2014_10
特許番号
US08865920B2

関連ノート

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