Potassium Carbonate → 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde

HRID 53952

反応式

HRID 53952 の反応式
[Br:1][C:2]1[CH:9]=[C:6]([CH:7]=[O:8])[C:5]([OH:10])=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:17][N:18]([CH3:22])[C:19](Cl)=[S:20]>CC(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:10][C:19](=[S:20])[N:18]([CH3:22])[CH3:17])=[C:6]([CH:9]=1)[CH:7]=[O:8]

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 27871Dimethylthiocarbamoyl chlorideHCID 728635-Bromosalicylaldehyde

生成物 1

HCID 212515955-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde収率 78.9%

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

8.13 g of 5-bromosalicylaldehyde was dissolved in 100 ml of acetone, followed by the addition of 6.7 g of anhydrous potassium carbonate. With stirring at room temperature, 5.0 g of N,N-dimethylthiocarbamoyl chloride was added to the above solution, and the stirring was continued for two hours. The resulting reaction solution was poured into ice water, and crystals thus precipitated were collected by filtration, and dried to obtain 9.2 g of 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde.

後処理

  1. customThe resulting reaction solution
  2. customthus precipitated
  3. filtrationwere collected by filtration
  4. customdried

出典と根拠

ORDレコード
ord-aa605a4ee8c24f2dab9b671f6dc79aa2
出典データセット
uspto-grants-1997_04
特許番号
US05620991

関連ノート

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