化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → 2-(Pyrimidin-4-yl)benzoic acid hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methyl 2-(pyrimidin-4-yl)benzoate | HCID 86680852 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-(Pyrimidin-4-yl)benzoic acid hydrochloride | HCID 86680853 | — |
反応手順
A mixture of methyl 2-(pyrimidin-4-yl)benzoate (0.49 g), acetic acid (2.0 mL) and 6 N hydrochloric acid (10 mL) was heated under reflux for 5 hr. The solvent was evaporated under reduced pressure, and the obtained residue was washed with ethyl acetate to give the title compound (0.45 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08871766B2 |
| 出典データセット | uspto-grants-2014_10 |
| ORD ID | ord-cc4be7e183604fe9ba2a4ce2aab13dc7 |
| 出典メモ | uspto-grants-2014_10 |