化工社化工社 化学情報印刷レポート · 研究参考用
4-Nitrophenyl methyl sulfide → 4-(Methylthio)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Nitrophenyl methyl sulfide | HCID 96109 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Nickel | HCID 935 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-(Methylthio)aniline | HCID 66038 | 92.7% |
反応手順
A suspension of 1-(methylsulfanyl)-4-nitrobenzene (10.5 g, 0.062 mol) and Raney nickel (5 g) in methanol (250 ml) was hydrogenated in a round flask equipped with a balloon filled with hydrogen at room temperature for 16 hours. The resulting mixture was filtered and concentrated in vacuo to afford 8.0 g of 4-(methylsulfanyl)aniline as colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08871756B2 |
| 出典データセット | uspto-grants-2014_10 |
| ORD ID | ord-2fca2c1116f94fabaf60c743e89bd88f |
| 出典メモ | uspto-grants-2014_10 |