4-Chloro-5-iodo-2-methylbenzoic acid → 4-Chloro-5-formyl-2-methylbenzoic acid

反応式

C1(C2C([CH:11]=[O:12])=CC(C(N3CCC(C4C=CC(C#N)=CC=4)CC3)=O)=C(C)C=2)CCC1.[Cl:30][C:31]1[C:39](I)=[CH:38][C:34]([C:35]([OH:37])=[O:36])=[C:33]([CH3:41])[CH:32]=1.C1(C2C(C=O)=CC(C(O)=O)=C(C)C=2)CCC1>>[Cl:30][C:31]1[C:39]([CH:11]=[O:12])=[CH:38][C:34]([C:35]([OH:37])=[O:36])=[C:33]([CH3:41])[CH:32]=1

参加物

反応物 3

HCID 682889484-Chloro-5-iodo-2-methylbenzoic acid2 回

HCID 866725464-Cyclobutyl-5-formyl-2-methylbenzoic acid

HCID 866725474-(1-(4-Cyclobutyl-5-formyl-2-methylbenzoyl)piperidin-4-yl)benzonitrile

生成物 1

HCID 866725494-Chloro-5-formyl-2-methylbenzoic acid

実験手順

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 392.2, except 4-chloro-5-iodo-2-methylbenzoic acid (compound 471.1) was used in place of 4-cyclobutyl-5-iodo-2-methylbenzoic acid (compound 392.1).

出典と根拠

ORDレコード: ord-b2a401a5e5244c3f9aaed7fb4875d884
出典データセット: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08871790B2

反応ノート

読み込み中…

参加物