化工社化工社 化学情報印刷レポート · 研究参考用
tert-Butyl 3-ethynylphenylcarbamate → Methyl [7-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-5-nitro-2-oxo-1,3-benzoxazol-3(2H)-yl]acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl 3-ethynylphenylcarbamate | HCID 11275982 | — |
| 反応物 | Methyl (7-iodo-5-nitro-2-oxo-1,3-benzoxazol-3(2H)-yl)acetate | HCID 57962495 | — |
| 生成物 | Methyl [7-({3-[(tert-butoxycarbonyl)amino]phenyl}ethynyl)-5-nitro-2-oxo-1,3-benzoxazol-3(2H)-yl]acetate | HCID 57961919 | — |
反応手順
The desired compound was prepared according to the procedure of Example B5, step C, using methyl (7-iodo-5-nitro-2-oxo-1,3-benzoxazol-3(2H)-yl)acetate and tert-butyl (3-ethynylphenyl)carbamate as the starting materials in quantitative yield. LCMS for C23H21N3O8Na (M+Na)+: m/z=490.0.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08871753B2 |
| 出典データセット | uspto-grants-2014_10 |
| ORD ID | ord-55ecf3e132b74632a4eb979f444b4758 |
| 出典メモ | uspto-grants-2014_10 |