化工社化工社 化学情報印刷レポート · 研究参考用
Aniline → Ethyl 3-anilinobut-2-enoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Ethyl Acetoacetate | HCID 8868 | — |
| 反応物 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | Ethyl 3-anilinobut-2-enoate | HCID 94928 | — |
反応手順
Aniline (0.20 mol) and ethylacetoacetate (0.20 mol) are mixed in toluene (200 mL) containing 0.04 g of p-toluenesulfonic acid-hydrate and heated at reflux under a water separator for one hour. The toluene is removed under vacuum to afford the ethyl-3-phenylaminobut-2-enoate which can be used as is for the preparation of the ethyl 2-methyl-3-quinolinecarboxylate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04656283 |
| 出典データセット | uspto-grants-1987_04 |
| ORD ID | ord-c2fa03bdf09e4696bdc72a952c4a4034 |
| 出典メモ | uspto-grants-1987_04 |