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Diethyl Ether → Ethyl (6-methoxy-1h-indol-3-yl)(oxo)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Ether | HCID 3283 | — |
| 反応物 | Oxalyl chloride | HCID 65578 | — |
| 反応物 | 6-Methoxy-1H-indole | HCID 76659 | — |
| 生成物 | Ethyl (6-methoxy-1h-indol-3-yl)(oxo)acetate | HCID 19958885 | — |
反応手順
7.5 cm3 of oxalyl chloride are added dropwise, under argon and over a period of 30 minutes, to a solution of 8.3 g of 6-methoxyindole, prepared in accordance with the process described by P. L. Feldman and H. Rapoport, Synthesis, (1986), 736, in 100 cm3 of anhydrous diethyl ether. After stirring for two hours, the precipitate formed is separated by filtration and then suspended in 200 cm3 of ethanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05622957 |
| 出典データセット | uspto-grants-1997_04 |
| ORD ID | ord-791a3c08f9704f98b7d1984cadf6dec0 |
| 出典メモ | uspto-grants-1997_04 |