1-(4-Chlorophenyl)cyclopentanecarboxylic acid → 1-(p-Chlorophenyl)cyclopentanemethanol

HRID 54262

反応式

HRID 54262 の反応式
[H-].[Al+3].[Li+].[H-].[H-].[H-].[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2([C:19](O)=[O:20])[CH2:18][CH2:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1>C(OCC)C>[Cl:7][C:8]1[CH:9]=[CH:10][C:11]([C:14]2([CH2:19][OH:20])[CH2:18][CH2:17][CH2:16][CH2:15]2)=[CH:12][CH:13]=1

参加物

4

反応物 2

HCID 974471-(4-Chlorophenyl)cyclopentanecarboxylic acidHCID 21226445Aluminium lithium hydride

生成物 1

HCID 27240171-(p-Chlorophenyl)cyclopentanemethanol

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

This compound is prepared in a manner analogous to that of Step A of Example 4, using 2.4 grams (0.06.3 mole) of lithium aluminum hydride, 21.8 grams (0.097 mole) of 1-(4-chlorophenyl)-1-cyclopentanecarboxylic acid (commercially available) in about 300 mL of diethyl ether, yielding [1-(4-chlorophenyl)-1-cyclopentyl]methanol.

後処理

  1. customThis compound is prepared in a manner analogous to that of Step A of Example 4

出典と根拠

ORDレコード
ord-652a0256dd35408ca4d952359e96b9c1
出典データセット
uspto-grants-1997_04
特許番号
US05622954

関連ノート

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