Benzaldehyde → Diphenylmethyl 7-benzylideneamino-3-chloromethyl-3-cephem-4-carboxylate

反応式

[NH2:1][CH:2]1[C:27](=[O:28])[N:4]2[C:5]([C:11]([O:13][CH:14]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)=[O:12])=[C:6]([CH2:9][Cl:10])[CH2:7][S:8][C@H:3]12.[CH:29](=O)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[CH:29](=[N:1][CH:2]1[C:27](=[O:28])[N:4]2[C:5]([C:11]([O:13][CH:14]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)=[O:12])=[C:6]([CH2:9][Cl:10])[CH2:7][S:8][C@H:3]12)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1

参加物

反応物 2

HCID 240Benzaldehyde

HCID 13239626Benzhydryl 7-Amino-3-chloromethyl-3-cephem-4-carboxylate

生成物 1

HCID 13850802Diphenylmethyl 7-benzylideneamino-3-chloromethyl-3-cephem-4-carboxylate

実験手順

reacting diphenylmethyl 7-amino-3-chloromethyl-3-cephem-4-carboxylate (free base form) with benzaldehyde to form the Schiff's base, i.e. diphenylmethyl 7-benzylideneamino-3-chloromethyl-3-cephem-4-carboxylate,

出典と根拠

ORDレコード: ord-362c3cfb953e432eb0d6184690f87dc1
出典データセット: uspto-grants-1987_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04659812

反応ノート

読み込み中…