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Water → Chrysanthemic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Chrysanthemic acid, cis-(-)- | HCID 20755 | — |
| 触媒 | tert-Butyl hydroperoxide | HCID 6410 | — |
| 触媒 | Bromhydrol | HCID 166749 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | Chrysanthemic Acid | HCID 2743 | 95.5% |
反応手順
In a 50 ml flask, there were charged (-)-cis-chrysanthemic acid (2.0 g), dioxane (17.5) and t-butyl hydroperoxide (0.011 g) under nitrogen. A solution of aluminum bromide (0.032 g) in dioxane (0.5 g) was added thereto at 15°-20° C. with stirring. After 30 minutes, water (0.5 g) was added to the reaction mixture with stirring. The reaction mixture was treated in the same manner as described in Example 1 and 1.91 g of chrysanthemic acid was obtained. The composition was as follows: (+)-cis, 3.3%; (-)-cis, 4.2%; (+)-trans, 46.2%; (-)-trans, 46.2%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04659864 |
| 出典データセット | uspto-grants-1987_04 |
| ORD ID | ord-8736bbb119b442fea09ceae2ca173bdd |
| 出典メモ | uspto-grants-1987_04 |