Methanol → HCID 13423729、化合物

HRID 543380ノート

反応式

HRID 543380 の反応式
[C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH3:17])(=[O:16])=[O:15])[C:5]=1[OH:18])([OH:3])=[O:2].S(=O)(=O)(O)O.[CH3:24]O>>[CH3:24][O:2][C:1]([C:4]1[CH:9]=[C:8]([C:10]([CH3:13])([CH3:12])[CH3:11])[CH:7]=[C:6]([S:14]([CH3:17])(=[O:16])=[O:15])[C:5]=1[OH:18])=[O:3]

参加物

4

反応物 3

HCID 887MethanolHCID 1118Sulfuric AcidHCID 13423728HCID 13423728、化合物

生成物 1

HCID 13423729HCID 13423729、化合物

実験手順

1.0 g (0.003 mol) of 2-carboxy-4-(1,1-dimethylethyl)-6-methylsulfonylphenol prepared in Example 3 is dissolved in 6 ml of methanol, and heated under reflux with 0.1 ml of concentrated sulfuric acid for 2 days. The mixture is poured onto ice-water, and this is extracted with ethyl acetate, the solvent is removed in vacuo and the residue is subjected to chromatography on silica gel using ethyl acetate/toluene 4:1 as the eluting agent.

後処理

  1. temperatureheated
  2. additionThe mixture is poured onto ice-water
  3. extractionthis is extracted with ethyl acetate
  4. customthe solvent is removed in vacuo

出典と根拠

ORDレコード
ord-c15f472ec7f346ed9c3ce48356232004
出典データセット
uspto-grants-1987_04
特許番号
US04661636

反応ノート

読み込み中…