Ammonia → 5-(Tert-butyl)-2-methoxybenzenesulfonamide
反応式
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13](Cl)(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3].[NH3:17]>CC(C)=O>[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:13]([NH2:17])(=[O:15])=[O:14])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1)([CH3:4])[CH3:3]参加物
4
実験手順
25.3 g (0.1 mol) of 3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride are dissolved in a little acetone and slowly added dropwise to 100 ml of concentrated ammonia solution at room temperature. The mixture is stirred at room temperature for 30 minutes and then poured onto ice-water. After acidification with concentrated hydrochloric acid, the product is filtered off with suction. Isopropanol is used for recrystallization. White crystals of melting point 156°-158° C.
後処理
- additionpoured onto ice-water
- filtrationAfter acidification with concentrated hydrochloric acid, the product is filtered off with suction
- customIsopropanol is used for recrystallization
出典と根拠
- ORDレコード
- ord-19009a8660254981a33a23cf4fadc1e1
- 出典データセット
- uspto-grants-1987_04
- 特許番号
- US04661636
反応ノート
読み込み中…