4-Chloro-alpha-methylstyrene → 4-Chlorocumene

HRID 543869

反応式

HRID 543869 の反応式
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([CH3:8])=[CH2:7])=[CH:4][CH:3]=1.[H][H]>[Pt]=O.C(O)C>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([CH:6]([CH3:8])[CH3:7])=[CH:4][CH:3]=1

参加物

5

反応物 2

HCID 743814-Chloro-alpha-methylstyreneHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 174934-Chlorocumene収率 74%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 702Ethanol溶媒

実験手順

A mixture of p-chloro-α-methylstyrene (15.7 g, 204 mmole), 20 milligrams (mg) platinum oxide, and 20 ml absolute ethanol was shaken on a Paar Hydrogenator for about 8 hours, beginning with an initial hydrogen pressure of 42 pounds-per-square-inch (psi). During this procedure, an additional 14 psi of hydrogen were added to the Hydrogenator reservoir. The mixture was then filtered and the solvent removed by careful distillation at atmospheric pressure. The residual material resulting was distilled using a water aspirator vacuum to yield 12.69 g (74% yield) of p-chlorocumene (bp 69°-74° C.).

後処理

  1. filtrationThe mixture was then filtered
  2. customthe solvent removed by careful distillation at atmospheric pressure
  3. customThe residual material resulting
  4. distillationwas distilled

出典と根拠

ORDレコード
ord-bbeb382fa30e424ebb0024583d6546bf
出典データセット
uspto-grants-1984_05
特許番号
US04447542

関連ノート

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