Hydrochloric Acid → 6-(2-Chlorophenyl)-4-oxo-4H-pyran-2-carboxylic acid
反応式
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:13][C:12]([C:14]([O:16]CC)=[O:15])=[CH:11][C:10](=[O:19])[CH:9]=2)=[CH:4][CH:3]=1.[ClH:20]>>[Cl:20][C:6]1[CH:7]=[CH:2][CH:3]=[CH:4][C:5]=1[C:8]1[O:13][C:12]([C:14]([OH:16])=[O:15])=[CH:11][C:10](=[O:19])[CH:9]=1参加物
3
実験手順
A mixture of ethyl 6-(4-chlorophenyl)-4-oxo-4H-pyran-2-carboxylate (3.9 g) and concentrated hydrochloric acid (40 ml) was heated under reflux for 2 hours. The reactant dissolved on warming and a solid began to precipitate. Water (40 ml) was added to the cooled mixture and the resulting buff solid yielded the title product as off-white needles (mp 241°-246° C. with decomposition).
後処理
- temperaturewas heated
- temperatureunder reflux for 2 hours
- dissolutionThe reactant dissolved
- temperatureon warming
- customto precipitate
- additionWater (40 ml) was added to the cooled mixture
出典と根拠
- ORDレコード
- ord-d99296df734f4604afff7b50eda18bce
- 出典データセット
- uspto-grants-1984_05
- 特許番号
- US04448787
反応ノート
読み込み中…