(2,4,6-Trichlorophenyl)hydrazine → HCID 70512904、化合物

HRID 544194

反応式

HRID 544194 の反応式
[C:1]([C:3](=[CH:12]OCC)[C:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:5])#[N:2].[Cl:16][C:17]1[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]([Cl:24])[C:18]=1[NH:25][NH2:26]>C(O)C.C1(C)C=CC=CC=1>[C:1]([C:3](=[CH:12][NH:26][NH:25][C:18]1[C:17]([Cl:16])=[CH:22][C:21]([Cl:23])=[CH:20][C:19]=1[Cl:24])[C:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])=[O:5])#[N:2]

参加物

4

反応物 2

HCID 79234(2,4,6-Trichlorophenyl)hydrazineHCID 230015ethyl N-(2-cyano-3-ethoxyacryloyl)carbamate

生成物 1

HCID 70512904HCID 70512904、化合物

試薬・触媒・溶媒 1

HCID 21863594Toluene ethanol溶媒

実験手順

Four grams (18.9 mmol) of α-cyano-β-ethoxy-N-ethoxycarbonylacrylamide is dissolved in hot ethanol/toluene. To this is added, portionwise, 4 g of 2,4,6-trichlorophenylhydrazine. The mixture is heated to reflux for three days. Cooling of the mixture and evaporation of the solvent gives the crude product, which is recrystallized from ethanol (3X) to yield α-cyano-β-(2,4,6-trichlorophenylhydrazino)-N-ethoxycarbonylacrylamide, m.p.=161° (dec.).

後処理

  1. additionTo this is added
  2. temperatureThe mixture is heated
  3. temperatureto reflux for three days
  4. temperatureCooling of the mixture and evaporation of the solvent
  5. customgives the crude product, which
  6. customis recrystallized from ethanol (3X)

出典と根拠

ORDレコード
ord-9bb6b37eb2dc4b28a309695713d62952
出典データセット
uspto-grants-1984_05
特許番号
US04448961

関連ノート

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