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Diazomethane → Methyl 10-undecynoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diazomethane | HCID 9550 | — |
| 反応物 | 10-Undecynoic acid | HCID 31039 | — |
| 反応物 | Boronic Acid | HCID 61668 | — |
| 反応物 | Benzcatechinborane | HCID 6327445 | — |
| 反応物 | Sodium Erythorbate | HCID 23683938 | — |
| 生成物 | Methyl 10-undecynoate | HCID 554128 | — |
反応手順
Methyl 10-undecynoate was prepared via the reaction of 10-undecynoic acid (Farchan) with diazomethane. The ester (1.6 g, 8 mmole) was hydroborated with catecholborane. The yield of the boronic acid was 1.7 g (87%); mp 48.5-50; mass spectrum, 316.9 (calcd. m/e316.1); NMR (CDCl3) 1.3 δ(broad s, 12H, alkane), 2.35 (broad envelope, 4H, --CH2CH=,--CH2CO2), 3.6 (s, 3H, --OCH3), 5.38 (d, 1H, --C=CHB, J=17 Hz), 6.4 (m, 1H, --CH=CHB).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04450149 |
| 出典データセット | uspto-grants-1984_05 |
| ORD ID | ord-0630dd4c43e442a49b4f19b40fa9c4ce |
| 出典メモ | uspto-grants-1984_05 |