反応式
[Cl:1][C:2]1[CH:10]=[C:9]([Cl:11])[CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][N:6]2[C@@H:12]1[O:29][C@H:28]([CH2:30][O:31]C(=O)C)[C@@H:23]([O:24]C(=O)C)[C@H:18]([O:19]C(=O)C)[C@H:13]1[O:14]C(=O)C.[CH2:35]([O:37][C:38]1[CH:46]=[CH:45][C:41]([C:42](Cl)=O)=[CH:40][CH:39]=1)[CH3:36]>>[Cl:11][C:9]1[CH:10]=[C:2]([Cl:1])[CH:3]=[C:7]2[C:8]=1[C:4]([CH2:42][C:41]1[CH:45]=[CH:46][C:38]([O:37][CH2:35][CH3:36])=[CH:39][CH:40]=1)=[CH:5][N:6]2[C@@H:12]1[O:29][C@H:28]([CH2:30][OH:31])[C@@H:23]([OH:24])[C@H:18]([OH:19])[C@H:13]1[OH:14]参加物
3
実験手順
The above 4,6-dichloro-1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-indole and 4-ethoxybenzoyl chloride were treated in a manner similar to Example 3 to give the titled compound, 4,6-dichloro-3-(4-ethoxyphenylmethyl)-1-(β-D-glucopyranosyl)-indole as a colorless powder. APCI-Mass m/Z 499/501 (M+NH4). 1H-NMR (DMSO-d6) δ 1.29 (t, J=7.0 Hz, 3H), 3.15-3.52 (m, 4H), 3.58 (m, 1H), 3.67 (m, 1H), 3.97 (q, J=6.9 Hz, 2H), 4.17 (s, 2H), 4.54 (t, J=5.6 Hz, 1H), 5.10 (d, J=5.3 Hz, 1H), 5.15 (d, J=5.1 Hz, 1H), 5.21 (d, J=5.8 Hz, 1H), 5.45 (d, J=9.0 Hz, 1H), 6.81 (d, J=8.5 Hz, 2H), 7.11 (m, 3H), 7.26 (s, 1H), 7.71 (d, J=1.1 Hz, 1H).
出典と根拠
- ORDレコード
- ord-04efc9b6eacb48dbb58185625763e600
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07935674B2
関連ノート
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