Benzenemethanol, 3-(2-quinolinylmethoxy)- → 2-(3-Chloromethylphenoxy)methylquinoline
反応式
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[CH2:16]O.[Cl:21]C1C=C2C(C=CC(COC3C=CC(CO)=CC=3)=N2)=CC=1>>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[CH2:16][Cl:21]参加物
3
実験手順
The procedure from Example 6, part B was used except 3-(quinolin-2-ylmethoxy)benzyl alcohol was substituted for 4-(7-chloroquinolin-2-ylmethoxy)benzyl alcohol. The intermediate was obtained in 72% yield: mp 39°-43° C.
後処理
- customThe intermediate was obtained in 72% yield
出典と根拠
- ORDレコード
- ord-3d167a1e51a64edb81a0a6863312ee2c
- 出典データセット
- uspto-grants-1997_04
- 特許番号
- US05622969
反応ノート
読み込み中…