Leu-Enkephalin → L-Leucine

反応式

N[C@H](C(NCC(NCC(N[C@H](C([NH:32][C@H:33]([C:38]([OH:40])=[O:39])[CH2:34][CH:35]([CH3:37])[CH3:36])=O)CC1C=CC=CC=1)=O)=O)=O)CC1C=CC(O)=CC=1>P([O-])([O-])([O-])=O>[NH2:32][C@H:33]([C:38]([OH:40])=[O:39])[CH2:34][CH:35]([CH3:37])[CH3:36]

参加物

実験手順

The degradation H-Tyr-Gly-Gly-Phe-Leu-OH (SEQ ID NO: 12) (˜1.8×10−4 M) in 50 mM phosphate buffer solutions of pH 7.4 containing carboxypeptidase A (1 U/ml) was studied as described above. The pseudo first-order rate constant for the degradation was estimated to 9.8×10−1 min−1 and the corresponding half-life calculated to 0.7 min as previously described.

後処理

wait−1 and the corresponding half-life calculated to 0.7 min

出典と根拠

ORDレコード: ord-19dff3bc3a7c449d9a8970df8df95bcc
出典データセット: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07935786B2

反応ノート

読み込み中…

参加物

反応物 1

HCID 461776Leu-Enkephalin

生成物 1

HCID 6106L-Leucine

試薬・触媒・溶媒 1

HCID 1061Phosphate溶媒

実験手順

後処理

wait−1 and the corresponding half-life calculated to 0.7 min

出典と根拠

ORDレコード: ord-19dff3bc3a7c449d9a8970df8df95bcc
出典データセット: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07935786B2

反応ノート

読み込み中…