1-(diphenylmethyl)-3-(5-hydroxy-2,3-dihydro-1-benzofuran-6-yl)-1,3-dihydro-2H-indol-2-one → 1-(diphenylmethyl)-3-(6-hydroxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-3-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one
反応式
C1(C(C2C=CC=CC=2)N2C3C(=CC=CC=3)C(C3C(O)=CC4C[CH2:22][O:23]C=4C=3)C2=O)C=CC=CC=1.[C:34]1([CH:40]([C:63]2[CH:68]=[CH:67][CH:66]=[CH:65][CH:64]=2)[N:41]2[C:49]3[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=3)[CH:43]([C:50]3[C:51]([OH:61])=[CH:52][C:53]4[O:57][CH2:56][C:55]([CH3:59])([CH3:58])[C:54]=4[CH:60]=3)[C:42]2=[O:62])[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1>>[C:63]1([CH:40]([C:34]2[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=2)[N:41]2[C:49]3[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=3)[C:43]([C:50]3[C:51]([OH:61])=[CH:52][C:53]4[O:57][CH2:56][C:55]([CH3:58])([CH3:59])[C:54]=4[CH:60]=3)([CH2:22][OH:23])[C:42]2=[O:62])[CH:68]=[CH:67][CH:66]=[CH:65][CH:64]=1参加物
3
反応物 2
生成物 1
実験手順
Following the procedure as described in PREPARATION 26C, and making non-critical variations to replace 1-(diphenylmethyl)-3-(5-hydroxy-2,3-dihydro-1-benzofuran-6-yl)-1,3-dihydro-2H-indol-2-one with 1-(diphenylmethyl)-3-(6-hydroxy-3,3-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one, the title compound was obtained: MS (ES+) m/z 492.5 (M+1)