Acetic Acid → 2-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone

HRID 54587

反応式

HRID 54587 の反応式
[C:1]1(=[O:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[C:12]([C:16]1[CH:23]=[CH:22][C:19]([CH:20]=O)=[CH:18][CH:17]=1)([CH3:15])([CH3:14])[CH3:13].[OH-].[K+].C(O)(=O)C>CO.O>[C:12]([C:16]1[CH:17]=[CH:18][C:19]([CH:20]=[C:2]2[CH2:3][CH2:4][C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[C:1]2=[O:11])=[CH:22][CH:23]=1)([CH3:15])([CH3:13])[CH3:14]

参加物

7

反応物 4

HCID 176Acetic AcidHCID 107241-TetraloneHCID 14797Potassium HydroxideHCID 703244-tert-Butylbenzaldehyde

生成物 1

HCID 35712132-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

A mixture of 3,4-dihydro-1(2H)-naphthalenone (4.5 g) and 4-tert-butylbenzaldehyde (5.0 g) was stirred with a solution of 4% potassium hydroxide in methanol (100 ml) for 64 hours at room temperature. The mixture was neutralised with glacial acetic acid, followed by dilution with water (100 ml). The resulting copious white precipitate was filtered off, washed with water and dried in vacuo to give 2-(4-tert-butylbenzylidene)-3,4-dihydro-1(2H)-naphthalenone.

後処理

  1. filtrationThe resulting copious white precipitate was filtered off
  2. washwashed with water
  3. customdried in vacuo

出典と根拠

ORDレコード
ord-392e6da757734f54a4b9ebfe00572a19
出典データセット
uspto-grants-1997_04
特許番号
US05622987

関連ノート

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