化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → (2Z)-2-hydroxyimino-5-methoxy-3H-inden-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Butyl nitrite | HCID 10996 | — |
| 反応物 | 5-Methoxyindan-1-one | HCID 78787 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | (2Z)-2-hydroxyimino-5-methoxy-3H-inden-1-one | HCID 6399792 | — |
反応手順
To a solution of 5-(methyloxy)-2,3-dihydro-1H-inden-1-one (1.0 g, 6.2 mmol) in methanol (15 mL) at 40 degrees Centigrade was added n-butyl nitrite (0.8 mL, 6.25 mmol) followed by concentrated HCl (0.6 mL). The reaction was stirred for 30 min during which time a precipitate formed, collected, dried and used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07939528B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-75d441e8924d412ea6701019e5b749d4 |
| 出典メモ | uspto-grants-2011_05 |