化工社化工社 化学情報印刷レポート · 研究参考用
3-(2-Bromoacetyl)benzonitrile → (RS)-2-[2-(3-Cyano-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(2-Bromoacetyl)benzonitrile | HCID 2735867 | — |
| 反応物 | 1-Boc-2-Piperidineacetic Acid | HCID 5058536 | — |
| 生成物 | (RS)-2-[2-(3-Cyano-phenyl)-2-oxo-ethoxycarbonylmethyl]-piperidine-1-carboxylic tert butyl ester | HCID 86629012 | 82.7% |
反応手順
The title compound (1.51 g) was prepared from (RS)-2-carboxymethyl-piperidine-1-carboxylic acid tert butyl ester (1.15 g) and 2-bromo-3′-cyanoacetophenone (1.06 g) according to the method of description 36.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07943645B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-5cf07779291941ef8ce7e5d981a0c0f0 |
| 出典メモ | uspto-grants-2011_05 |