Methyl Acrylate → (E)-3-{4-[4-methyl-1-(2-pyrazolo[1,5-a]pyridin-3-yl-ethyl)-piperazin-2-yl]-phenyl}-acrylic acid methyl ester

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][N:12]([CH3:14])[CH2:11][CH2:10][N:9]2[CH2:15][CH2:16][C:17]2[CH:18]=[N:19][N:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=23)=[CH:4][CH:3]=1.[C:26]([O:30][CH3:31])(=[O:29])[CH:27]=[CH2:28].CN(C1CCCCC1)C1CCCCC1>O1CCOCC1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd].C(P(C(C)(C)C)C(C)(C)C)(C)(C)C.F[B-](F)(F)F>[CH3:31][O:30][C:26](=[O:29])/[CH:27]=[CH:28]/[C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:13][N:12]([CH3:14])[CH2:11][CH2:10][N:9]2[CH2:15][CH2:16][C:17]2[CH:18]=[N:19][N:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=23)=[CH:4][CH:3]=1