Dichloromethane → 2-(5-Methylfuran-2-yl)ethan-1-amine

HRID 550622

反応式

HRID 550622 の反応式
C([N:3]([CH2:6][CH3:7])CC)C.[C:8]([O:11][C:12](=O)[CH3:13])(=O)[CH3:9].[CH2:15](Cl)Cl>>[CH3:9][C:8]1[O:11][C:12]([CH2:7][CH2:6][NH2:3])=[CH:13][CH:15]=1

参加物

4

反応物 3

HCID 6344DichloromethaneHCID 7918Acetic AnhydrideHCID 8471Triethylamine

生成物 1

HCID 149337782-(5-Methylfuran-2-yl)ethan-1-amine

実験手順

To a solution of the amine C (1 mol) in CH2Cl2 (approx. 10 ml per 1 g of the starting compound) triethylamine (1.1 mol) and acetic anhydride (1.2 mol) were added. The reaction mixture is stirred at room temperature for 1 h and concentrated on rotary evaporator. The residue is triturated with hexane, filtered, washed with hexane to give a crystalline compound in good yields.

後処理

  1. concentrationconcentrated on rotary evaporator
  2. customThe residue is triturated with hexane
  3. filtrationfiltered
  4. washwashed with hexane
  5. customto give a crystalline compound in good yields

出典と根拠

ORDレコード
ord-fecd54f676ab45f1abfe9f1bb1307074
出典データセット
uspto-grants-2011_05
特許番号
US07947689B2

関連ノート

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