Sodium triacetoxyborohydride → 2,3,4-Trimethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

反応式

[CH3:1][C:2]1[S:10][C:9]2[CH2:8][CH2:7][N:6]=[C:5]([CH3:11])[C:4]=2[C:3]=1[CH3:12].C(O[BH-](OC(=O)C)OC(=O)C)(=O)C.[Na+]>>[CH3:1][C:2]1[S:10][C:9]2[CH2:8][CH2:7][NH:6][CH:5]([CH3:11])[C:4]=2[C:3]=1[CH3:12]

参加物

反応物 2

HCID 5049666Sodium triacetoxyborohydride

HCID 596630912,3,4-Trimethyl-6,7-dihydrothieno[3,2-c]pyridine

生成物 1

HCID 596630822,3,4-Trimethyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine収率 14%

実験手順

In close analogy to the procedure described above, 2,3,4-Trimethyl-6,7-dihydrothieno[3,2-c]pyridine is reacted with sodium triacetoxyborohydride to provide the title compound.

出典と根拠

ORDレコード: ord-e724f928d94742a6afdc4bb7851b2e10
出典データセット: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07947689B2

反応ノート

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