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3-(Trifluoromethyl)-4-methylphenyl Isocyanate → 3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(Trifluoromethyl)-4-methylphenyl Isocyanate | HCID 3449170 | — |
| 反応物 | 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | HCID 57445354 | — |
| 生成物 | 3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide | HCID 57445310 | — |
反応手順
47.1 mg of solid white 3-{4-[3-(4-methyl-3-trifluoromethylphenyl)ureido]-phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide and 4-methyl-3-trifluoromethylphenyl isocyanate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07947706B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-053d109c931048a086dbfe010156ea74 |
| 出典メモ | uspto-grants-2011_05 |