Potassium Hydroxide → 4-(4,4-Dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoic acid

HRID 551238ノート

反応式

HRID 551238 の反応式
[CH3:1][C:2]1([CH3:19])[CH2:6][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([O:13]C)=[O:12])=[CH:9][C:8]=2[CH3:17])[C:4](=[O:18])[NH:3]1.[OH-].[K+]>CO.O>[CH3:1][C:2]1([CH3:19])[CH2:6][N:5]([C:7]2[CH:16]=[CH:15][C:10]([C:11]([OH:13])=[O:12])=[CH:9][C:8]=2[CH3:17])[C:4](=[O:18])[NH:3]1

参加物

5

反応物 2

HCID 14797Potassium HydroxideHCID 67048320Methyl 4-(4,4-dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoate

生成物 1

HCID 667315354-(4,4-Dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoic acid

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒

実験手順

2.70 g (10.3 mmol) methyl 4-(4,4-dimethyl-2-oxo-imidazolidin-1-yl)-3-methyl-benzoate are suspended in 75 ml of methanol and combined with a solution of 1.68 g (30.0 mmol) potassium hydroxide in 10 ml of water. It is stirred for 3 hours at ambient temperature and then evaporated down i. vac. The aqueous residue is diluted with water, acidified with 1-molar hydrochloric acid and the precipitate obtained is suction filtered, washed with water and dried.

後処理

  1. customevaporated down i
  2. additionThe aqueous residue is diluted with water
  3. customthe precipitate obtained
  4. filtrationfiltered
  5. washwashed with water
  6. customdried

出典と根拠

ORDレコード
ord-5f51c8622a2344d68896fece1cb35113
出典データセット
uspto-grants-2011_05
特許番号
US07947700B2

反応ノート

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