Toluene → HCID 86646155、化合物
反応式
[CH2:1]([CH:4]1[CH2:8][CH2:7][O:6][CH:5]1[OH:9])[CH:2]=[CH2:3].[CH2:10]([O:12]C(P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=O)C.[C:34]1([CH3:40])C=CC=C[CH:35]=1>>[OH:12][CH2:10][CH2:3][CH:2]([CH2:40][CH:34]=[CH2:35])/[CH:1]=[CH:4]/[C:5]([O:6][CH2:7][CH3:8])=[O:9]参加物
4
実験手順
3-allyl-tetrahydrofuran-2-ol (18 g, 140 mmol) and ethoxycarbonyl triphenylphosphorane (35 g, 104 mmol) were stirred overnight in toluene (200 mL). The reaction solution was concentrated, and the residue was purified by silica gel column chromatography to obtain the compound of interest as an oil substance (15.8 g, 61.1%).
後処理
- concentrationThe reaction solution was concentrated
- customthe residue was purified by silica gel column chromatography
- customto obtain the compound of interest as an oil substance (15.8 g, 61.1%)
出典と根拠
- ORDレコード
- ord-27af5f9a4e42434abf0c6c363f642844
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07947738B2
反応ノート
読み込み中…