Sodium Sulfate → 2,2-Dimethyl-5-(2-(2-(dimethylamino)ethoxy)ethyl-imino)-3-hexanone

反応式

[CH3:1][C:2]([CH3:10])([C:4](=[O:9])[CH2:5][C:6](=O)[CH3:7])[CH3:3].[CH3:11][N:12]([CH3:19])[CH2:13][CH2:14][O:15][CH2:16][CH2:17][NH2:18].S([O-])([O-])(=O)=O.[Na+].[Na+]>C(OCC)C>[CH3:1][C:2]([CH3:10])([C:4](=[O:9])[CH2:5][C:6](=[N:18][CH2:17][CH2:16][O:15][CH2:14][CH2:13][N:12]([CH3:19])[CH3:11])[CH3:7])[CH3:3]

参加物

実験手順

In a 100 mL round bottom flask equipped with a magnetic stirrer, 8 g 2,2-dimethylhexane-3,5-dione was combined with 1.1 equivalents of 2-(2-(dimethylamino)ethoxy)ethylamine, anhydrous sodium sulfate and anhydrous diethyl ether and stirred over three days under nitrogen. The ether was removed on a rotary evaporator and the residue was vacuum distilled through a Vigreux column to yield 9.7 g of product.