Benzaldehyde → 2-(2-Benzylidenehydrazino)benzoic acid

HRID 552089

反応式

HRID 552089 の反応式
Cl.[NH:2]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([OH:8])=[O:7])[NH2:3].[CH:13](=O)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>O.C(O)C>[CH:13](=[N:3][NH:2][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([OH:8])=[O:7])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

5

反応物 2

HCID 240BenzaldehydeHCID 104169Benzoic acid, 2-hydrazinyl-, hydrochloride (1:1)

生成物 1

HCID 2226872-(2-Benzylidenehydrazino)benzoic acid収率 69%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒2 回HCID 962Water溶媒

実験手順

To a solution of 2-hydrazino-benzoic acid mono hydrochloric acid salt (13.66 g, 72.42 mmol) dissolved in water (580 mL) and ethanol (125 mL) was added a solution of benzaldehyde (7.35 mL, 72.42 mmol) in ethanol (20 mL) dropwise at room temperature. The reaction mixture was stirred at room temperature for an additional 3 hours. The resulting solid was collected by filtration and dried in a vacuum oven to provide 12.0 g (69%) of 2-(N′-benzylidene-hydrazino)-benzoic acid as a yellow solid.

後処理

  1. filtrationThe resulting solid was collected by filtration
  2. customdried in a vacuum oven

出典と根拠

ORDレコード
ord-f6f1e2feb8db4ee79020f74dde7b0dd4
出典データセット
uspto-grants-2011_05
特許番号
US07951800B2

関連ノート

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