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3-Bromo-2-methylpyridine → 2,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (4-methyl-thiazol-2-yl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Bromo-2-methylpyridine | HCID 1201003 | — |
| 反応物 | 2-Pyridinecarboxamide, 6-methyl-N-(4-methyl-2-thiazolyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)- | HCID 49760412 | — |
| 生成物 | 2,6'-Dimethyl-[3,4']bipyridinyl-2'-carboxylic acid (4-methyl-thiazol-2-yl)-amide | HCID 24820887 | — |
反応手順
The title compound, was prepared from 6-Methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxa-borolan-2-yl)-pyridine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide in accordance with the general method of example 131, step 2 using 3-Bromo-2-methylpyridine instead of 3-Trifluoromethyl-5-bromopyridine to yield the final compound as a white solid, MS (ISP): m/e=325.2 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07951824B2 |
| 出典データセット | uspto-grants-2011_05 |
| ORD ID | ord-9d61e994e52744b0a2af13ccf6e482e1 |
| 出典メモ | uspto-grants-2011_05 |