3-Aminopyridine → 5-Fluoro-6'-methyl-[3,4']bipyridinyl-2'-carboxylic acid pyridin-3-ylamide
反応式
C(O[C:4]([C:6]1[CH:11]=[C:10]([C:12]2[CH:13]=[N:14][CH:15]=[C:16]([F:18])[CH:17]=2)[CH:9]=[C:8]([CH3:19])[N:7]=1)=[O:5])C.[NH2:20][C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1>>[N:23]1[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][C:4]([C:6]2[CH:11]=[C:10]([C:12]3[CH:13]=[N:14][CH:15]=[C:16]([F:18])[CH:17]=3)[CH:9]=[C:8]([CH3:19])[N:7]=2)=[O:5])[CH:22]=1参加物
3
実験手順
The title compound, was prepared from 5-Fluoro-6′-methyl-[3,4′]bipyridinyl-2′-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 3-Aminopyridine instead of 3-chloroaniline to yield the final compound as a white crystalline, MS (ISP): m/e=309.3 (M+H)+.
出典と根拠
- ORDレコード
- ord-4ad337bcfe6f49ba826c6e033d9158d4
- 出典データセット
- uspto-grants-2011_05
- 特許番号
- US07951824B2
反応ノート
読み込み中…