2,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone → Wrypvzdhvrcrog-xjksgupxsa-

HRID 552778ノート

反応式

HRID 552778 の反応式
[C:1]([O:9][C@@H:10]1[C@H:16](OC(=O)C2C=CC=CC=2)[C@@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C@H:14]([CH3:35])[O:13][C:11]1=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CCN(CC)CC.C(Cl)(Cl)Cl>[C:1]([O:9][C:10]1[C:11]([O:13][C@@H:14]([CH3:35])[C@H:15]([O:26][C:27](=[O:34])[C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH:16]=1)=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 1

HCID 112368422,3,4-Tri-o-benzoyl-l-rhamnono-1,5-lactone

生成物 1

HCID 11221893Wrypvzdhvrcrog-xjksgupxsa-収率 65%

試薬・触媒・溶媒 1

HCID 18929042Triethylamine chloroform溶媒

実験手順

The compound (VII) (13.2 g, 27.8 mmol) is dissolved in Et3N:CHCl3 (1:4, 500 ml) under N2 current and stirred for 16 hours at a room temperature. After the reaction is finished, it is washed by water. An organic layer is dried using anhydrous MgSO4. The solution is vacuum concentrated and then the compound (VIII) (6.37 g, 65%) is isolated using flash column chromatography (toluene/EtOAc, 10:1, v/v).

後処理

  1. washit is washed by water
  2. customAn organic layer is dried
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-783d157677b94e8e8c941b17c8656409
出典データセット
uspto-grants-2011_05
特許番号
US07951839B2

反応ノート

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