N,N'-Diphenylformamidine → 3-methyl-2-((E)-2-phenylamino-vinyl)-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

HRID 553022

反応式

HRID 553022 の反応式
[Na+:1].[CH3:2][C:3]1[C:11]([CH3:19])([CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:17])=[O:16])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]=1[CH2:20][CH2:21][CH2:22][S:23]([OH:26])(=[O:25])=[O:24].[C:27]1([NH:33][CH:34]=NC2C=CC=CC=2)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>CO>[Na+:1].[CH3:19][C:11]1([CH2:12][CH2:13][CH2:14][S:15]([OH:18])(=[O:16])=[O:17])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N+:4]([CH2:20][CH2:21][CH2:22][S:23]([OH:26])(=[O:24])=[O:25])=[C:3]1/[CH:2]=[CH:34]/[NH:33][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

参加物

4

反応物 2

HCID 94888N,N'-DiphenylformamidineHCID 866399822,3-dimethyl-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

生成物 1

HCID 866399813-methyl-2-((E)-2-phenylamino-vinyl)-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

0.822 g (2 mmol) 2,3-dimethyl-1,3-bis-(3-sulfo-propyl)-3H-indolium sodium salt 7 and 0.49 g (2.5 mmol) N,N′-diphenyl-formamidine are dissolved in 20 ml methanol and stirred for about four hours under reflux. The solvent is removed in vacuum after cooling to room temperature. The residue is washed carefully with ethyl acetate. A dark yellow solid is obtained which is processed without further purification.

後処理

  1. temperatureunder reflux
  2. customThe solvent is removed in vacuum
  3. washThe residue is washed carefully with ethyl acetate
  4. customA dark yellow solid is obtained which
  5. customis processed without further purification

出典と根拠

ORDレコード
ord-1fb798efe658416a8eba39e595841675
出典データセット
uspto-grants-2011_05
特許番号
US07951959B2

関連ノート

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