Ethanamine, 2,2,2-trifluoro- → [2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-(2,2,2-trifluoro-ethyl)-amine

反応式

[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH:3]=O.[F:14][C:15]([F:19])([F:18])[CH2:16][NH2:17]>>[CH3:1][C:2]([N:6]1[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[N:8]=[CH:7]1)([CH3:5])[CH2:3][NH:17][CH2:16][C:15]([F:19])([F:18])[F:14]

参加物

反応物 2

HCID 9773Ethanamine, 2,2,2-trifluoro-

HCID 866008092-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde

生成物 1

HCID 67163871[2-Methyl-2-(4-nitro-imidazol-1-yl)-propyl]-(2,2,2-trifluoro-ethyl)-amine

実験手順

2-Methyl-2-(4-nitro-imidazol-1-yl)-propionaldehyde was reacted with 2,2,2-trifluoro-ethyl amine to provide the title compound: H1 NMR (400 MHz, CDCl3) 1.59 (s, 6H), 2.98 (s, 2H), 3.10 (m, 2H), 7.56 (s, 1H), 7.90 (s, 1H) MS m/z 267.3 (M+1).

出典と根拠

ORDレコード: ord-1a31f8eceef44bf18d2bcc0b04e650c7
出典データセット: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07951958B2

反応ノート

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