化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl chloroacetate → Ethyl sulfoacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl chloroacetate | HCID 7751 | — |
| 反応物 | Sodium Sulfite | HCID 24437 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Ethyl sulfoacetate | HCID 12216623 | 100.1% |
反応手順
To a solution of Na2SO3 (10 g, 79 mmol.) in 50 mL of H2O was added a solution of ethyl 2-chloroacetate (12.7 mL, 119 mmol.) in 55 mL of EtOH. The mixture was heated at reflux for 6 h, after which time all the volatiles were removed by evaporation under reduced pressure. The concentrated materials were dried to afford crude (ethoxycarbonyl)methanesulfonic acid (13.3 g, 100%) used directly without purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08048862B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-c88b6db0b6db47158d18750b41bcb397 |
| 出典メモ | uspto-grants-2011_11 |