化工社化工社 化学情報印刷レポート · 研究参考用
Tosylmethyl isocyanide → Ethyl 4-methyl-1h-pyrrole-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tosylmethyl isocyanide | HCID 161915 | — |
| 反応物 | Ethyl trans-crotonate | HCID 429065 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 生成物 | Ethyl 4-methyl-1h-pyrrole-3-carboxylate | HCID 235044 | 71.1% |
反応手順
Using p-toluenesulfonylmethyl isocyanide (8.55 g), ethyl crotonate (5.0 g) and potassium tert-butoxide (5.90 g), a procedure as in Reference Example 39 was performed to give the title compound as a pale-yellow solid (yield 4.77 g, 71%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08048909B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-c31a5c841b6e47ee8805ad48720a6c35 |
| 出典メモ | uspto-grants-2011_11 |