Tosylmethyl isocyanide → Methyl 4-ethyl-1H-pyrrole-3-carboxylate
反応式
C1(C)C=CC(S([CH2:10][N+:11]#[C-:12])(=O)=O)=CC=1.[C:14]([O:20][CH3:21])(=[O:19])[CH:15]=[CH:16][CH2:17][CH3:18].CC(C)([O-])C.[K+]>>[CH2:17]([C:16]1[C:15]([C:14]([O:20][CH3:21])=[O:19])=[CH:10][NH:11][CH:12]=1)[CH3:18]参加物
4
実験手順
Using p-toluenesulfonylmethyl isocyanide (10.1 g), methyl 2-pentenoate (6.01 g) and potassium tert-butoxide (7.01 g), a procedure as in Reference Example 39 was performed to give the title compound as pale-yellow crystals (yield 5.05 g, 64%).
出典と根拠
- ORDレコード
- ord-172882b642284e0bba6bb7c1b956104f
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08048909B2
反応ノート
読み込み中…