化工社化工社 化学情報印刷レポート · 研究参考用
HCID 12660316、化合物 → 2-Benzylphenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | HCID 12660316 | HCID 12660316 | — |
| 触媒 | Palladium hydroxide | HCID 9942167 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-Benzylphenol | HCID 24216 | 67% |
反応手順
To a solution of 2-(4-chlorobenzyl)phenol (618.5 mg, 2.83 mmol) in methanol (20 mL), a 20% palladium hydroxide catalyst (240 mg) was added. The mixture was stirred under a hydrogen atmosphere for three days, and then the catalyst was filtered off. The solvent was distilled under reduced pressure and the obtained residue was purified by silica gel column chromatography [developing solution=ethyl acetate:n-hexane (1:4)] to obtain the title compound (348.4 mg, 67%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08048897B2 |
| 出典データセット | uspto-grants-2011_11 |
| ORD ID | ord-882e0f4fdfcf4a8086b0b4f0864124f9 |
| 出典メモ | uspto-grants-2011_11 |