Glycine tert-butyl ester hydrochloride → HCID 57670929、化合物
反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:35][CH3:36])=[C:6]([CH:34]=1)[CH2:7][CH:8]1[C:14](=[O:15])[N:13]([C:16]([NH:18][CH:19]([CH2:31][CH3:32])[C:20]([NH:22]CC(OC(C)(C)C)=O)=[O:21])=[O:17])[CH2:12][C:11](=[O:33])[NH:10][CH2:9]1.Cl.C(OC(=O)CN)(C)(C)C.[C:47]([O:56]C(C)(C)C)(=[O:55])[C:48]1[C:49](=[CH:51][CH:52]=[CH:53][CH:54]=1)N>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:35][CH3:36])=[C:6]([CH:34]=1)[CH2:7][CH:8]1[C:14](=[O:15])[N:13]([C:16]([NH:18][C@H:19]([CH2:31][CH3:32])[C:20]([NH:22][C:54]2[CH:53]=[CH:52][CH:51]=[CH:49][C:48]=2[C:47]([OH:56])=[O:55])=[O:21])=[O:17])[CH2:12][C:11](=[O:33])[NH:10][CH2:9]1参加物
4
実験手順
Instead of the starting material compound of Example 220, that is, the glycine tert-butyl ester hydrochloride, tert-butyl anthranilate was used for the similar procedure as in Example 220 and Example 245 to obtain the title compound.