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HRID 555750作成日：2026年10月27日

Bromoacetonitrile → (4-Pyridin-4-ylmethyl-piperazin-1-yl)-acetonitrile

https://huagongshe.com/reaction/555750

反応式

関与物質

役割名称HCID仕込み量
反応物BromoacetonitrileHCID 11534—
反応物1-((Pyridin-4-yl)methyl)piperazineHCID 808715—
生成物(4-Pyridin-4-ylmethyl-piperazin-1-yl)-acetonitrileHCID 63337270—

反応手順

The title compound is synthesized by coupling of 1-Pyridin-4-ylmethyl-piperazine (commercially available from ABCR GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=217.2: 1HNMR(CDCl3) 8.55 (d, 2H), 7.25 (d, 2H), 3.50 (s, 4H), 2.70-2.40 (m, 8H).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08053457B2
出典データセットuspto-grants-2011_11
ORD IDord-4257399ccb734528a88461f5610ed262
出典メモuspto-grants-2011_11